master's thesis
Blood disorders and manifestations on the oral mucosa
case report

Anja Povalec (2013)
Sveučilište u Rijeci
Medicinski fakultet
Katedra za oralnu medicinu i parodontologiju
Metadata
TitleKrvne bolesti i pojavnosti na oralnoj sluznici : prikaz slučaja
AuthorAnja Povalec
Mentor(s)Sonja Pezelj-Ribarić (thesis advisor)
Abstract
Bolesti krvotvornog sustava dijele se po poremećajima pojedinih krvotvornih loza. Najčešće su definirane kao: bolesti eritrocita, bolesti trombocita te bolesti leukocita Bolesti eritrocita su anemije i policitemija. Anemični poremećaji povezani s oralnim znakovima i simptomima uključuju anemiju uzrokovanu željezom, megaloblastične anemije, hemolitičke anemije, hemoglobinopatije i aplastičnu anemiju. U manifestacije se uključuje bljedoća usnica i sluznice, crven, gladak i atrofičan jezik, žutica, deformacije maksile, karijes, gingivitis, disfagija, parestezije mentalnog živca i druge. Policitemija karakterizirana je ljubičastocrvenim promjenama sluznice, krvarenjima. Bolesti trombocita su trombocitopenija i poremećaji hemostaze. U bolesnika s trombocitopenijom mogu se naći hemoragijske bule, edematozna, hiperemična gingiva koja spontano krvari, neugodan zadah. Poremećaji hemostaze povezani s oralnim znakovima i simptomima uključuju hemofiliju A, hemofiliju B te Von Willebrandovu bolest. Glavno kliničko obilježje tih bolesti je krvarenje. Bolesti leukocita su neutropenija i leukemija. Oralne manifestacije neutropenije su infekcije, parodontne bolesti i ulceracije sluznice usne šupljine. Oralne manifestacije leukemije javljaju se zbog same bolesti (bujanje gingive, destrukcija alveolarne kosti, pomicanje zuba, bljedilo sluznica, cijanoza, spontana krvarenja, petehije, ekhimoze, hematomi) i zbog liječenja bolesti (mukozitis, kserostomija, bakterijske, gljivične infekcije, osteoradionekroza).
Keywordsanaemia hematologic diseases leukaemia oral manifestation
Parallel title (English)Blood disorders and manifestations on the oral mucosa : case report
Committee MembersSonja Pezelj-Ribarić
Miranda Muhvić-Urek
Ivana Brekalo-Pršo
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za oralnu medicinu i parodontologiju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Medicine
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeDental Medicine
Academic title abbreviationdr. med. dent.
Genremaster's thesis
Language Croatian
Defense date2013-09-26
Parallel abstract (English)
The classification of blood system diseases is based on changes within individual groups of blood cells. They are most commonly defined as: diseases of erythrocytes, diseases of platelets and diseases of leukocytes. The diseases of erythrocytes are anaemias and polycythemia. Anaemia disorders resulting in oral symptoms and signs include iron deficiency anaemia, megaloblastic anaemia, haemolytic anaemia, hemoglobinopathies and aplastic anaemia. Manifestations include pale lips and pale mucous membranes, red, smooth and atrophic tongue, jaundice, deformations of maxilla, caries, gingivitis, dysphagia, paresthesias of mental nerve and others. Polycythemia is characterised by purple-red changes of the mucous membranes with bleeds. The diseases of platelets are thrombocytopenia and bleeding disorders. In patients with thrombocytopenia haemorrhage bullae, oedematous, hyperemic gingiva that bleeds spontaneously, as well as bad breath, may be found. Bleeding disorders resulting in oral signs and symptoms include haemophilia A, haemophilia B and Von Willebrand disease. The main clinical sign of these diseases is bleeding. The diseases of leukocytes are neutropenia and leukaemia. Oral manifestations of neutropenia are infections, periodontal diseases and ulcerations on the mucous membrane of the oral cavity. Oral manifestations of leukaemia occur due to a disease (gingival enlargement, destruction of the alveolar bone, teeth movement, pale mucous membranes, cyanosis, spontaneous bleeds, petechiae, ecchymoses, hematomas) or due to the treatment of a disease (mucositis, xerostomia, bacterial infections, fungal infections, osteoradionecrosis).
Parallel keywords (Croatian)anemija hematološke bolesti leukemija oralne manifestacije
Resource typetext
Access conditionAccess restricted to students and staff of home institution
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:748650
CommitterBosa Licul