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master's thesis
Suvremeni pristup u liječenju mioma
2018. urn:nbn:hr:184:336075
Oroshi, Aurela
University of Rijeka
Faculty of Medicine
Department of Gynaecology and Obstetrics

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Oroshi, A. (2018). Suvremeni pristup u liječenju mioma (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:336075

Oroshi, Aurela. "Suvremeni pristup u liječenju mioma." Master's thesis, University of Rijeka, Faculty of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:184:336075

Oroshi, Aurela. "Suvremeni pristup u liječenju mioma." Master's thesis, University of Rijeka, Faculty of Medicine, 2018. https://urn.nsk.hr/urn:nbn:hr:184:336075

Oroshi, A. (2018). 'Suvremeni pristup u liječenju mioma', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 18 December 2024, https://urn.nsk.hr/urn:nbn:hr:184:336075

Oroshi A. Suvremeni pristup u liječenju mioma [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2018 [cited 2024 December 18] Available at: https://urn.nsk.hr/urn:nbn:hr:184:336075

A. Oroshi, "Suvremeni pristup u liječenju mioma", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:184:336075

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Metadata
TitleSuvremeni pristup u liječenju mioma
AuthorAurela Oroshi
MentorAlemka Brnčić-Fischer (mentor)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Gynaecology and Obstetrics)
Rijeka
Defense date and country2018-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract
Miomi su najčešći dobroćudni tumori maternice u žena reproduktivne dobi. Obzirom na broj, lokalizaciju i veličinu uzrokuju simptome poput obilnog produženog krvarenja, bolova i pritiska u zdjelici i okolnim organima te neplodnosti. Zlatni standard u dijagnostici je ultrazvuk. Liječenje može biti medikamentozno, operativno i radiološko. Medikamentozno liječenje uključuje hormonsku terapiju kao preoperatvinu pripremu, a najznačajniji su analozi GnRH i selektivni modulatori progesteronskih receptora (SPRM). Predstavnik SPRM-a, ulipristal-acetat pokazuje vrlo dobre, dugotrajnije rezultate liječenja, sa manje nuspojava u odnosu na analoge GnRH. Operativne metode jesu miomektomija i histerektomija. Miomektomija je poštedniji operativni zahvat, indiciran i kod žena koje planiraju trudnoću, dok je histerektomija radikalni zahvat kojim se u potpunosti uklanjaju simptomi uzrokovani miomima. Laparoskopskom tehnikom postiže se manja postoperativna bol, kraće trajanje hospitalizacije, bolji kozmetički učinak i brži povratak svakodnevnim aktivnostima. Minimalno invazivne tehnike poput embolizacije uterine arterije, ablacije mioma fokusirajućim ultrazvučnim valovima pod kontrolom magnetske rezonancije i radiofrekventna volumetrijska termička ablacija mioma novije su metode koje imaju svoja ograničenja.
Abstract (english)
Myomas are the most common benign uterine tumors in women of reproductive age. Due to the their number, localization and size myomas cause symptoms such as abundant prolonged bleeding, pain and pressure in the pelvis, surrounding organs, and infertility. The gold standard in diagnosis is ultrasound. Treatment may be medical, surgical and radiological. Medical treatment includes hormone therapy as a preoperative preparation, the most significant are GnRH agonists and selective progesterone receptor modulators (SPRMs). Representative of SPRM, ulipristal acetate shows very good, long-lasting treatment results, with fewer side effects compared to GnRH analogs. Surgical techniques are myomectomy and hysterectomy. Miomectomy is conservative surgical procedure, indicated also in women who want to conceive. Hysterectomy is a radical procedure that completely removes symptoms caused by fibroids. Laparoscopic technique achieves lower postoperative pain, shorter hospitalization time, better cosmetic effect and faster return on daily activities. Minimally invasive techniques such as uterine artery embolization(UAE), highfrequency magnetic resonance-guided focused ultrasound surgery (MRgFUS), and radiofrequency volumetric thermal ablation (RFVTA) are new methods but day by day with less limitations.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:336075
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-12-06 15:14:39