Tuberculosis is a chronic, contagious disease caused by bacillus M. Tuberculosis. The disease primarily affects the lungs, but there is a possibility of a hematogenic spread, resulting in the involvement of any other organ, like urogenital system. Affecting the kidney, more precisely parenchyma is quite rare, something more often tuberculosis affect the lower part of the urinary system because of excretion through the tubule into the urinary tract, and also the genital part because of its good blood circulation. Symptoms are not specific, and they are often observed by random findings. Initially, the patient complains about frequent, painless urination, microhematuria and sterile pyuria. If the disease has progressed and spred on the bladder, the symptoms are more pronounced. General symptoms such as fever, exhaustion, weight loss are rare. If the disease is not recognized and timely treated there is possibility of complicatons on distant organs, such as meningoencephalitis. In further diagnosis we analyze urine on Mycobacterium tuberculosis which may be established by demonstration of tubercle bacili in the urine by acid- fast stain or PCR, if feasible. Furthermore, a safer and more accurate finding will enable us radiographic tools such as CT with contrast and ultrasound, but the CT provides a better anatomical presentation so it is preferred if it is feasible. Establishing a diagnosis of urogenital tuberculosis it is necessary to start immediately initial antituberculatory therapy, but if the lesions progress despite appropriate treatment, a further therapeutic procedure is early stenting or percutaneous nephrostomy. If disease is advanced, or to prevent further complications it is ordered surgical treatment which include nephrectomy, dilatation or reconstruction of ureteral stricture, and bladder augmentation.