prikaz prve stranice dokumenta Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response
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Scientific paper - review paper
Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response
Frontiers in Immunology, 2 (2011); 85. https://doi.org/10.3389/fimmu.2011.00085
Slavuljica, Irena; Krmpotić, Astrid; Jonjić, Stipan

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Slavuljica, I., Krmpotić, A. & Jonjić, S. (2011). Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response. Frontiers in Immunology, 2.. doi: 10.3389/fimmu.2011.00085

Slavuljica, Irena, et al. "Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response." Frontiers in Immunology, vol. 2, 2011. https://doi.org/10.3389/fimmu.2011.00085

Slavuljica, Irena, Astrid Krmpotić and Stipan Jonjić. "Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response." Frontiers in Immunology 2 (2011). https://doi.org/10.3389/fimmu.2011.00085

Slavuljica, I., Krmpotić, A. and Jonjić, S. (2011) 'Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response', Frontiers in Immunology, 2. doi: 10.3389/fimmu.2011.00085

Slavuljica I, Krmpotić A, Jonjić S. Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response. Frontiers in Immunology [Internet]. 2011 [cited 2024 December 25];2. doi: 10.3389/fimmu.2011.00085

I. Slavuljica, A. Krmpotić and S. Jonjić, "Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response", Frontiers in Immunology, vol. 2, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:996238. [Accessed: 25 December 2024]

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Metadata
Title (english)Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response
AuthorIrena Slavuljica
AuthorAstrid Krmpotić
AuthorStipan Jonjić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Histology and Embryology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
NKG2D is a potent activating receptor expressed on NK cells, NKT cells, γδ T cells, and CD8 T cells. NKG2D recognizes cell surface molecules structurally related to MHC class I proteins induced by infection or other type of cellular stress. The engagement of NKG2D leads to NK cell cytotoxicity and cytokine secretion or to a co-stimulation of CD8 T cells. Both human and mouse cytomegalovirus (CMV) have evolved numerous mechanisms to evade NKG2D-mediated immune response. This review describes the mechanisms used by CMV to inhibit NKG2D ligand expression and the recent advances in exploiting the NKG2D recognition pathway for mounting efficient and long-lasting immune response.
Keywords (english)
Languageenglish
Publication typeScientific paper - review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFrontiers in Immunology
Numberingvol. 2, 85
e-ISSN1664-3224
DOIhttps://doi.org/10.3389/fimmu.2011.00085
URN:NBNurn:nbn:hr:184:996238
Publication2011
ProjectNumber: 062-0621261-1263
Title (croatian): Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://journal.frontiersin.org/article/10.3389/fimmu.2011.00085/abstract
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-11-08 23:35:10