prikaz prve stranice dokumenta A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure
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Scientific paper - Original scientific paper
A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure
Acta Clinica Belgica, 73 (2018), 3; 199-206. https://doi.org/10.1080/17843286.2018.1483562
Dvornik, Štefica; Zaninović Jurjević, Teodora; Jurjević, Nikola; Lekić, Amalija; Zaputović, Luka

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Dvornik, Š., Zaninović Jurjević, T., Jurjević, N., Lekić, A. & Zaputović, L. (2018). A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure. Acta Clinica Belgica, 73. (3), 199-206. doi: 10.1080/17843286.2018.1483562

Dvornik, Štefica, et al. "A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure." Acta Clinica Belgica, vol. 73, no. 3, 2018, pp. 199-206. https://doi.org/10.1080/17843286.2018.1483562

Dvornik, Štefica, Teodora Zaninović Jurjević, Nikola Jurjević, Amalija Lekić and Luka Zaputović. "A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure." Acta Clinica Belgica 73, no. 3 (2018): 199-206. https://doi.org/10.1080/17843286.2018.1483562

Dvornik, Š., et al. (2018) 'A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure', Acta Clinica Belgica, 73(3), pp. 199-206. doi: 10.1080/17843286.2018.1483562

Dvornik Š, Zaninović Jurjević T, Jurjević N, Lekić A, Zaputović L. A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure. Acta Clinica Belgica [Internet]. 2018 [cited 2024 April 25];73(3):199-206. doi: 10.1080/17843286.2018.1483562

Š. Dvornik, T. Zaninović Jurjević, N. Jurjević, A. Lekić and L. Zaputović, "A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure", Acta Clinica Belgica, vol. 73, no. 3, pp. 199-206, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:870020. [Accessed: 25 April 2024]

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Metadata
Title (english)A simple prognostic model for assessing in-hospital mortality risk in patients with acutely decompensated heart failure
AuthorŠtefica Dvornik
AuthorTeodora Zaninović Jurjević
AuthorNikola Jurjević
AuthorAmalija Lekić
AuthorLuka Zaputović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Clinical Laboratory Diagnostics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background: An assessing of the in-hospital mortality risk for an emergency hospitalized patient with acutely decompensated heart failure (ADHF) is challenging task. Simple formula can help. Methods: On the base of six indicators identified in derivation group, simple formula for assessing the risk for in-hospital mortality of ADHF patients was derived and later tested in validation group. Results: The retrospective analysis of a derivation group (533 survivors, 121 deceased) identified six risk indicators: age, heart rate (HR), systolic blood pressure (SBP) and serum concentrations of urea, sodium (Na) and uric acid (UA). The final formula was created ([age/10]2 HR/SBP)+(Urea-Na/10)+UA/100 and formula result of 53 was established as cut-off result. In the derivation group, at the cut-off point of 53, area under the ROC curve (AUC) was 0.741 (95% CI 0.7010.776) ; with sensitivity 54% and specificity 83%. The discriminative capacity of the formula was significantly higher than each of its components. In the validation group of 591 patients (527 survived, 64 died) AUC was also 0.741 (95% CI 0.7060.774), sensitivity was 66% and specificity 76%. Positive predictive value (PPV) of the developed formula was modest (34%), but negative predictive value (NPV) was 95%. N-terminal pro-B type natriuretic peptide and troponin I were determined, but not included into formula. Conclusions: The developed formula enables simple, rapid and inexpensive risk assessment, but its disadvantage is a low PPV. However, a high NPV permits the identification of patients with a low risk of in-hospital mortality, which could lead to a more rational patient treatment.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Clinica Belgica
Numberingvol. 73, no. 3, pp. 199-206
p-ISSN1784-3286
e-ISSN2295-3337
DOIhttps://doi.org/10.1080/17843286.2018.1483562
URN:NBNurn:nbn:hr:184:870020
Publication2018
Document URLhttp://bib.irb.hr/942048
Document URLhttps://www.tandfonline.com/doi/full/10.1080/17843286.2018.1483562
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2018-06-15 16:35:54