prikaz prve stranice dokumenta USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA
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master's thesis
USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA
2017. urn:nbn:hr:184:463446
Bašić, Marcela
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Bašić, M. (2017). USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:463446

Bašić, Marcela. "USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA." Master's thesis, University of Rijeka, Faculty of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:184:463446

Bašić, Marcela. "USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA." Master's thesis, University of Rijeka, Faculty of Medicine, 2017. https://urn.nsk.hr/urn:nbn:hr:184:463446

Bašić, M. (2017). 'USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 12 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:463446

Bašić M. USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2017 [cited 2024 November 12] Available at: https://urn.nsk.hr/urn:nbn:hr:184:463446

M. Bašić, "USPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:184:463446

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Metadata
TitleUSPOREDBA UČINKOVITOSTI TOCILIZUMABA I TNF INHIBITORA U LIJEČENJU REUMATOIDNOGA ARTRITISA
Title (english)COMPARASION OF EFFICACY BETWEEN TOCILIZUMAB AND TNF INHIBITORS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
AuthorMarcela Bašić
MentorSrđan Novak (mentor)
Committee memberTea Schnurrer-Luke-Vrbanić (predsjednik povjerenstva)
Committee memberBrankica Mijandrušić-Sinčić (član povjerenstva)
Committee memberToni Valković (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2017-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Reumatoidini artritis je kompleksna upalna bolest i kao takva zahtjeva kompleksan način liječenja. Napredak medicine i razvoj biološke terapije doveo je do lakšeg postizanja remisije i kontrole same bolesti. U biološkom liječenju reumatoidnog artritisa danas se upotrebaljavaju lijekovi iz skupine TNF inhibitora te IL-6 inhibitor, tocilizumab. U našem istraživanju uspoređujudi bolesnike liječene tocilizumabom i TNF inhibitorima u prvoj liniji biološkog liječenja pokazali smo da primjenom tocilizumaba brže postiže remisija, te da tijekom 18 mjeseci biološkog liječenja TNF inhibitorima češdi prekid ili mjenjanje liječenja. Ipak potrebna su i druga istraživanja koja bi mogla potvrditi ili opovrgnuti ove rezultate.
Abstract (english)
Rheumatoid arthritis is complex, inflammatory disease and the main therapy has its own comlex element beacuse of that. Medical progress and development of biological therapy lead to easier way to achieve remission and compleate control of disease. Today in biological treatment of rheumatic arthritis it has been used TNF inhibtor drugs and IL-6 inhibitor, tocilizumab. Comparing patients treated with tocilizumab and TNF inhibitors as first line of biologicat therapy, in our research we have shown that application of tocilizumab has faster accomplishment of remission and within 18 months of biological treatment with TNF inhibitors there is more common abort and change of therapy. Nevertheless other research are needed to prove or deny this results.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:463446
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2017-11-24 12:50:36