prikaz prve stranice dokumenta Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice
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Scientific paper - Original scientific paper
Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice
Croatica Chemica Acta, 68 (1995), 3; 559-567. urn:nbn:hr:184:036413
Milin, Čedomila; Radošević-Stašić, Biserka; Verbanac, Donatella; Domitrović, Robert; Petković, Marija; Trobonjača, Zlatko; Ravlić-Gulan, Jagoda; Ćuk, Mira; Varljen, Jadranka; Rukavina, Daniel

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Milin, Č., Radošević Stašić, B., Verbanac, D., Domitrović, R., Petković, M., Trobonjača, Z. ... Rukavina, D. (1995). Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice. Croatica Chemica Acta, 68. (3), 559-567. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:036413

Milin, Čedomila, et al. "Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice." Croatica Chemica Acta, vol. 68, no. 3, 1995, pp. 559-567. https://urn.nsk.hr/urn:nbn:hr:184:036413

Milin, Čedomila, Biserka Radošević Stašić, Donatella Verbanac, Robert Domitrović, Marija Petković, Zlatko Trobonjača, Jagoda Ravlić Gulan, Mira Ćuk, Jadranka Varljen and Daniel Rukavina. "Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice." Croatica Chemica Acta 68, no. 3 (1995): 559-567. https://urn.nsk.hr/urn:nbn:hr:184:036413

Milin, Č., et al. (1995) 'Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice', Croatica Chemica Acta, 68(3), pp. 559-567. Available at: https://urn.nsk.hr/urn:nbn:hr:184:036413 (Accessed 22 April 2024)

Milin Č, Radošević Stašić B, Verbanac D, Domitrović R, Petković M, Trobonjača Z, and sur.. Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice. Croatica Chemica Acta [Internet]. 1995 September 01 [cited 2024 April 22];68(3):559-567. Available at: https://urn.nsk.hr/urn:nbn:hr:184:036413

Č. Milin, et al., "Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice", Croatica Chemica Acta, vol. 68, no. 3, pp. 559-567, September 1995. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:036413. [Accessed: 22 April 2024]

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Title (english)Activation of Zinc-Dependent Hepato-Thymic Axis During Liver Regeneration in Hepatectomized Mice
AuthorČedomila Milin
AuthorBiserka Radošević-Stašić
AuthorDonatella Verbanac
AuthorRobert Domitrović
AuthorMarija Petković
AuthorZlatko Trobonjača
AuthorJagoda Ravlić-Gulan
AuthorMira Ćuk
AuthorJadranka Varljen
AuthorDaniel Rukavina
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Zinc is an essential trace element for many biological functions including the processes of normal growth and functioning of the lymphatic system. In this study, we estimated the role of the thymus in liver regeneration following a 1/3 partial hepatectomy (pHx) as well as the role of zinc ions in these processes. The data have shown that fast liver growth is followed by marked hypoplasia of the thymus and a difference in the proportion of the T-cell phenotype (increase of double negative CD4_CD8_ and single positive CD4+ and CDB+ cells, and decrease of double positive CD4+CD8+ cells). Simultaneously, a significant increase of tissue zind concentration was found both in liver and in thymus. The most pronounced increase was recorded 24 hours (liver) and 48 hours (thymus) after pHx. These results pointed to the possibility that the accumulation of zinc in both organs might be linked to the activity of growth factors which are activated by pHx. Furthermore, it is possible that activation of zinc-dependent thymic hormones or interleukins facilitates the zinc formation of T-lymophocytes with morphogenetic functions participating in the control of liver regeneration.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 68, no. 3, pp. 559-567
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:184:036413
Publication1995-09-01
Document URLhttp://hrcak.srce.hr/136715
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-09-19 21:38:12