prikaz prve stranice dokumenta BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder
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Scientific paper - Original scientific paper
BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder
Prostaglandins, Leukotrienes and Essential Fatty Acids, 78 (2008), 6; 351-360. urn:nbn:hr:184:616267
Nadalin, Sergej; Rubeša, Gordana; Giacometti, Jasminka; Vulin, Mirjana; Tomljanović, Draško; Vraneković, Jadranka; Kapović, Miljenko; Buretić-Tomljanović, Alena

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Nadalin, S., Rubeša, G., Giacometti, J., Vulin, M., Tomljanović, D., Vraneković, J. ... Buretić Tomljanović, A. (2008). BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder. Prostaglandins, Leukotrienes and Essential Fatty Acids, 78. (6), 351-360. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:616267

Nadalin, Sergej, et al. "BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder." Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 78, no. 6, 2008, pp. 351-360. https://urn.nsk.hr/urn:nbn:hr:184:616267

Nadalin, Sergej, Gordana Rubeša, Jasminka Giacometti, Mirjana Vulin, Draško Tomljanović, Jadranka Vraneković, Miljenko Kapović and Alena Buretić Tomljanović. "BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder." Prostaglandins, Leukotrienes and Essential Fatty Acids 78, no. 6 (2008): 351-360. https://urn.nsk.hr/urn:nbn:hr:184:616267

Nadalin, S., et al. (2008) 'BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder', Prostaglandins, Leukotrienes and Essential Fatty Acids, 78(6), pp. 351-360. Available at: https://urn.nsk.hr/urn:nbn:hr:184:616267 (Accessed 18 February 2025)

Nadalin S, Rubeša G, Giacometti J, Vulin M, Tomljanović D, Vraneković J, and sur.. BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder. Prostaglandins, Leukotrienes and Essential Fatty Acids [Internet]. 2008 June [cited 2025 February 18];78(6):351-360. Available at: https://urn.nsk.hr/urn:nbn:hr:184:616267

S. Nadalin, et al., "BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder", Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 78, no. 6, pp. 351-360, June 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:616267. [Accessed: 18 February 2025]

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Metadata
Title (english)BanI polymorphism of cytosolic phospholipase A2 gene is associated with age at onset in male patients with schizophrenia and schizoaffective disorder
AuthorSergej Nadalin
AuthorGordana Rubeša
AuthorJasminka Giacometti
AuthorMirjana Vulin
AuthorDraško Tomljanović
AuthorJadranka Vraneković
AuthorMiljenko Kapović
AuthorAlena Buretić-Tomljanović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
The enzymes phospholipases A2 are believed to be involved in the pathology of schizophrenia. We investigated allelic and genotype frequencies of PLA2G4A BanI polymorphism and the rs4375 in PLA2G6A in Croatian schizophrenic patients (n=81) and controls (n=182), using PCR/RFLP. Genotype and allelic frequencies of both loci, alone or in combination did not show significant difference (χ2-test). Allele-wise and genotype-wise meta-analyses of BanI polymorphism in case–control and family-based studies also revealed no significant association with schizophrenia. Multiple logistic regression analyses revealed statistically significant association between several items from PANSS general psychopathology scale and BanI polymorphism in PLA2G4A. BanI polymorphism further showed a significant impact on mean age of the onset of disease in males (βA1=0.351, P=0.021; Spearman's rA1=0.391, P=0.010) indicating lower mean age at admission in homozygous A2A2 males.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleProstaglandins, Leukotrienes and Essential Fatty Acids
Numberingvol. 78, no. 6, pp. 351-360
p-ISSN0952-3278
URN:NBNurn:nbn:hr:184:616267
Publication2008-06
ProjectNumber: 062-0982522-0369
Title (croatian): Genetika metabolizma fosfolipida u shizofreniji
Title (english): Genetics of phospholipid metabolism in schizophrenia
Leader: Alena Buretić-Tomljanović
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://www.sciencedirect.com/science/article/pii/S0952327808000537
Type of resourceText
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2017-05-16 07:49:53