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Professional paper - Review paper
Akutna limfoblastična leukemija u djece
Medicina Fluminensis : Medicina Fluminensis, 47 (2011), 4; 343-352. urn:nbn:hr:184:899902
Roganović, Jelena

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Roganović, J. (2011). Akutna limfoblastična leukemija u djece. Medicina Fluminensis : Medicina Fluminensis, 47. (4), 343-352. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:899902

Roganović, Jelena. "Akutna limfoblastična leukemija u djece." Medicina Fluminensis : Medicina Fluminensis, vol. 47, no. 4, 2011, pp. 343-352. https://urn.nsk.hr/urn:nbn:hr:184:899902

Roganović, Jelena. "Akutna limfoblastična leukemija u djece." Medicina Fluminensis : Medicina Fluminensis 47, no. 4 (2011): 343-352. https://urn.nsk.hr/urn:nbn:hr:184:899902

Roganović, J. (2011) 'Akutna limfoblastična leukemija u djece', Medicina Fluminensis : Medicina Fluminensis, 47(4), pp. 343-352. Available at: https://urn.nsk.hr/urn:nbn:hr:184:899902 (Accessed 22 November 2024)

Roganović J. Akutna limfoblastična leukemija u djece. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2011 December 01 [cited 2024 November 22];47(4):343-352. Available at: https://urn.nsk.hr/urn:nbn:hr:184:899902

J. Roganović, "Akutna limfoblastična leukemija u djece", Medicina Fluminensis : Medicina Fluminensis, vol. 47, no. 4, pp. 343-352, December 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:899902. [Accessed: 22 November 2024]

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Metadata
Title (croatian)Akutna limfoblastična leukemija u djece
Title (english)Acute lymphoblastic leukemia in children
AuthorJelena Roganović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pediatrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract (croatian)
Akutna limfoblastična leukemija najčešća je maligna bolest u djece. Primjena terapije prilagođene skupinama rizika rezultirala je izlječenjem u otprilike 80 % bolesnika, čime spada u jednu od najuspješnijih priča u povijesti onkologije. Poboljšanom sustavnom i intratekalnom terapijom danas je u većine djece moguće izostaviti profilaktičko zračenje središnjeg živčanog sustava. Kontinuirani napredak farmakogenomike dat će u bliskoj budućnosti nov uvid u pedijatrijsku leukemogenezu i izbor optimalne terapije. Kroz to vrijeme potrebno je imati na umu kasne učinke terapije u značajnog dijela preživjelih, te intenzivirati preventivne mjere i njihovo rano otkrivanje.
Abstract (english)
Acute lymphoblastic leukemia is the most common pediatric malignancy. The implementation of risk-adapted treatment has secured a cure rate of approximately 80 %, and as such is one of the most successful stories in the history of oncology. The improved systemic and intrathecal chemotherapy has now enabled the safe omission of the prophylactic cranial irradiation in the vast majority of patients. Continuous advances in pharmacogenomics will provide new insights in pediatric leukemogenesis, and the optimal treatment in the near future. Meanwhile, important to have in mind that a significant fraction of leukemia survivors will have late therapy-related effects, and intensify preventive strategies and their early detection.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 47, no. 4, pp. 343-352
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:899902
Publication2011-12-01
Document URLhttp://hrcak.srce.hr/76665
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-05-11 14:14:14