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Scientific paper - Case study
Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja
Medicina Fluminensis : Medicina Fluminensis, 54 (2018), 4; 438-441. https://doi.org/10.21860/medflum2018_207365
Nikić, Manca; Vuletić, Vladimira

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Nikić, M. & Vuletić, V. (2018). Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja. Medicina Fluminensis : Medicina Fluminensis, 54. (4), 438-441. doi: 10.21860/medflum2018_207365

Nikić, Manca and Vladimira Vuletić. "Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja." Medicina Fluminensis : Medicina Fluminensis, vol. 54, no. 4, 2018, pp. 438-441. https://doi.org/10.21860/medflum2018_207365

Nikić, Manca and Vladimira Vuletić. "Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja." Medicina Fluminensis : Medicina Fluminensis 54, no. 4 (2018): 438-441. https://doi.org/10.21860/medflum2018_207365

Nikić, M. and Vuletić, V. (2018) 'Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja', Medicina Fluminensis : Medicina Fluminensis, 54(4), pp. 438-441. doi: 10.21860/medflum2018_207365

Nikić M, Vuletić V. Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2018 December 01 [cited 2024 May 05];54(4):438-441. doi: 10.21860/medflum2018_207365

M. Nikić and V. Vuletić, "Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja", Medicina Fluminensis : Medicina Fluminensis, vol. 54, no. 4, pp. 438-441, December 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:252394. [Accessed: 05 May 2024]

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Title (croatian)Sindrom diskinezija-hiperpireksija – novo hitno stanje kod Parkinsonove bolesti: prikaz slučaja
Title (english)Dyskinesia-hyperpyrexia syndrome – a new medical emergency in Parkinson’s disease: case report
AuthorManca Nikić
AuthorVladimira Vuletić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Neurology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (croatian)
Cilj: Sindrom diskinezija-hiperpireksija hitno je stanje u Parkinsonovoj bolesti do kojeg dolazi zbog pretjerane dopaminergične stimulacije. Kolebanje koncentracije dopamina uzrokuje generalizirane atetotske diskinezije s izrazitom hipertermijom, rabdomiolizom te konfuznim stanjem. Cilj ovog rada jest prikazati slučaj bolesnika koji boluje od Parkinsonove bolesti, a prezentirao se diskinezijama i hiperpireksijom. Prikaz slučaja: Prikazujemo slučaj bolesnika u dobi od 55 godina koji je zatražio pomoć zbog visokog febriliteta i pogoršanja diskinezija u trajanju od 15 dana. Bolesnik je, usprkos detaljnom kliničkom pregledu i laboratorijskoj obradi, bio neprepoznat. U daljnjem tijeku liječenja stanje bolesnika se pogoršalo u vidu izrazite hiperpireksije uz razvoj respiratorne insuficijencije i cirkulacijske nestabilnosti. Nakon četiri tjedna liječenja u jedinici intenzivnog liječenja, bolesnik s teškom autonomnom disfunkcijom završio je smrtnim ishodom. Zaključak: Ovaj slučaj upućuje na važnost ranog prepoznavanja diskinezija i hiperpireksije kao hitnog stanja u bolesnika oboljelih od Parkinsonove bolesti s ciljem rane medikamentne potpore te sprječavanja po život opasnih posljedica.
Abstract (english)
Aim: Dyskinesia-hyperpyrexia syndrome is a rare case of medical emergency in Parkinson's disease caused by excessive dopaminergic stimulation. It is characterized with severe continuous dyskinesias associated with rhabdomyolysis, hyperthermia, and subsequent alteration of the mental state. The aim of this paper is to present a clinical case of a patient suffering from Parkinson's disease presenting with dyskinesia and hyperpyrexia. Case report: We present a case of a fifty-five-year-old patient who presented with fifteen-day high body temperature and worsening of dyskinesia. The patient, in spite of a detailed clinical examination and laboratory examination, was unidentified as such. In the further course of the treatment, the condition of the patient deteriorated in the sense of extreme hyperpyrexia with the development of respiratory insufficiency and circulatory instability. After four weeks of treatment in the Intensive Care Unit, a patient with severe autonomic dysfunction, passed away. Conclusion: This case points out the importance of early recognition of dyskinesia and hyperpyrexia as an emergency in Parkinson's disease with the aim of early medical support and the prevention of life-threatening consequences.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 54, no. 4, pp. 438-441
p-ISSN1847-6864
e-ISSN1848-1868
DOIhttps://doi.org/10.21860/medflum2018_207365
URN:NBNurn:nbn:hr:184:252394
Publication2018-12-01
Document URLhttps://hrcak.srce.hr/207365
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-12-03 16:24:15